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NDB ID: 6DCB    PDB ID: 6DCB 


Title:

STRUCTURE OF METHYLPHOSPHATE CAPPING ENZYME METHYLTRANSFERASE DOMAIN IN COMPLEX WITH 5' END OF 7SK RNA

Molecular Description:

7SK snRNA methylphosphate capping enzyme/RNA Complex

Deposited:

2018-05-04

Released:

2018-12-19

Nucleic Acid Sequence:

Click to show/hide 1 nucleic acid sequences

Protein Sequence:

Click to show/hide 1 protein sequences

Primary Citation:

Yang, Y., Eichhorn, C.D., Wang, Y., Cascio, D., Feigon, J.
Structural basis of 7SK RNA 5'-gamma-phosphate methylation and retention by MePCE. 
Nat. Chem. Biol., 15, pp. 132 - 140, 2019.

Experimental Information:

X-RAY DIFFRACTION

Space Group:

P 63

Cell Constants:

a = 118.28   b = 118.28   c = 78.63 (Ångstroms)

α = 90.0   β = 90.0   γ = 120.0 (degrees)

Refinement:

The structure was refined using the PHENIX program. The R value is 0.1619 for 42437 reflections in the resolution range 62.373 to 1.998 Ångstroms with Fobs >  1.37 sigma(Fobs) and with I >  0.0 sigma(I)