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NDB ID: 6EHT    PDB ID: 6EHT 


Title:

MODULATION OF PCNA SLIDING SURFACE BY P15PAF SUGGESTS A SUPPRESSIVE MECHANISM FOR CISPLATIN-INDUCED DNA LESION BYPASS BY POL ETA HOLOENZYME

Molecular Description:

Proliferating cell nuclear antigen/DNA Complex

Structural Keywords:

B DOUBLE HELIX

Nucleic Acid Sequence:

Click to show/hide 2 nucleic acid sequences

Protein Sequence:

Click to show/hide 3 protein sequences

Primary Citation:

De March, M., Barrera-Vilarmau, S., Crespan, E., Mentegari, E., Merino, N., Gonzalez-Magana, A., Romano-Moreno, M., Maga, G., Crehuet, R., Onesti, S., Blanco, F.J., De Biasio, A.
p15PAF binding to PCNA modulates the DNA sliding surface. 
Nucleic Acids Res., 46, pp. 9816 - 9828, 2018.

Experimental Information:

X-RAY DIFFRACTION

Space Group:

P 1 21 1

Cell Constants:

a = 75.993   b = 42.3   c = 141.827 (Ångstroms)

α = 90.0   β = 102.7   γ = 90.0 (degrees)

Refinement:

The structure was refined using the REFMAC program. The R value is 0.26401 for 13440 reflections in the resolution range 40.48 to 3.2 Ångstroms with Fobs >  0.0 sigma(Fobs) and with I >  0.0 sigma(I)