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NDB ID: 6ERP    PDB ID: 6ERP 


Title:

STRUCTURE OF THE HUMAN MITOCHONDRIAL TRANSCRIPTION INITIATION COMPLEX AT THE LSP PROMOTER

Molecular Description:

Transcription factor A
mitochondrial
DNA-directed RNA polymerase
mitochondrial
Dimethyladenosine transferase 2
mitochondrial/DNA Complex

Nucleic Acid Sequence:

Click to show/hide 2 nucleic acid sequences

Protein Sequence:

Click to show/hide 3 protein sequences

Primary Citation:

Hillen, H.S., Morozov, Y.I., Sarfallah, A., Temiakov, D., Cramer, P.
Structural Basis of Mitochondrial Transcription Initiation. 
Cell, 171, pp. 1072 - 1081.e10, 2017.

Experimental Information:

X-RAY DIFFRACTION

Space Group:

P 1 21 1

Cell Constants:

a = 103.91   b = 197.03   c = 137.21 (Ångstroms)

α = 90.0   β = 99.87   γ = 90.0 (degrees)

Refinement:

The structure was refined using the PHENIX program. The R value is 0.2721 for 31840 reflections in the resolution range 49.583 to 4.502 Ångstroms with Fobs >  1.33 sigma(Fobs) and with I >  0.0 sigma(I)