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NDB ID: 6F3C    PDB ID: 6F3C 


Title:

THE CYTOTOXIC [PT(H2BAPBPY)] PLATINUM COMPLEX INTERACTING WITH THE CGTACG HEXAMER

Molecular Description:

DNA (5'-D(*GP*TP*AP*CP*G)-3')

Deposited:

2017-11-28

Released:

2019-05-29

Structural Keywords:

B DOUBLE HELIX

Nucleic Acid Sequence:

Click to show/hide 2 nucleic acid sequences

Protein Sequence:

No Protein Sequence Found

Primary Citation:

van Rixel, V.H.S., Busemann, A., Wissingh, M.F., Hopkins, S.L., Siewert, B., van de Griend, C., Siegler, M.A., Marzo, T., Papi, F., Ferraroni, M., Gratteri, P., Bazzicalupi, C., Messori, L., Bonnet, S.
Induction of a Four-Way Junction Structure in the DNA Palindromic Hexanucleotide 5'-d(CGTACG)-3' by a Mononuclear Platinum Complex. 
Angew.Chem.Int.Ed.Engl., , pp. - , 2019.

Experimental Information:

X-RAY DIFFRACTION

Space Group:

P 32 2 1

Cell Constants:

a = 30.09   b = 30.09   c = 116.99 (Ångstroms)

α = 90.0   β = 90.0   γ = 120.0 (degrees)

Refinement:

The structure was refined using the REFMAC program. The R value is 0.261 for 2732 reflections in the resolution range 39.0 to 2.3 Ångstroms with Fobs >  0.0 sigma(Fobs) and with I >  0.0 sigma(I)