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NDB ID: 6FFR    PDB ID: 6FFR 


Title:

DNA-RNA HYBRID QUADRUPLEX WITH FLIPPED TETRAD

Molecular Description:

DNA/RNA (5'-R(*G)-D(P*GP*GP*AP*TP*GP*GP*GP*AP*CP*AP*CP*AP*GP*GP*GP*GP*AP*C)-R(P*G)-D(P*GP*G)-3')

Deposited:

2018-01-09

Released:

2018-09-26

Structural Keywords:

QUADRUPLE HELIX, HAIRPIN LOOP

Nucleic Acid Sequence:

Click to show/hide 1 nucleic acid sequences

Protein Sequence:

No Protein Sequence Found

Primary Citation:

Haase, L., Dickerhoff, J., Weisz, K.
DNA-RNA Hybrid Quadruplexes Reveal Interactions that Favor RNA Parallel Topologies. 
Chemistry, 24, pp. 15365 - 15371, 2018.

Experimental Information:

SOLUTION NMR

Number of Models:

Number of Models: 10 Structures

Sample Details:

10 mM potassium phosphate, 0.48 mM DNA/RNA (5'-R(*G)-D(P*GP*GP*AP*TP*GP*GP*GP*AP*CP*AP*CP*AP*GP*GP*GP*GP*AP*C)-R(P*G)-D(P*GP*G)-3'), 90% H2O/10% D2O 90% H2O/10% D2O