A Portal for Three-dimensional Structural Information about Nucleic Acids
As of 20-Feb-2019 number of released structures: 10049
Search for released structures

NDB ID: 6FHI    PDB ID: 6FHI 


Title:

CRYSTAL STRUCTURE OF BAT INFLUENZA A/H17N10 POLYMERASE WITH VIRAL RNA PROMOTER BOUND TO A 19-MER SERINE 5 PHOSPHORYLATED POL II CTD PEPTIDE WITH A TRUNCATED LINKER.

Molecular Description:

Polymerase acidic protein
RNA-directed RNA polymerase catalytic subunit
Polymerase basic protein 2/RNA Complex

Deposited:

2018-01-14

Released:

2019-01-30

Structural Keywords:

A DOUBLE HELIX

Nucleic Acid Sequence:

Click to show/hide 2 nucleic acid sequences

Protein Sequence:

Click to show/hide 4 protein sequences

Primary Citation:

Claron, M., Lukarska, M., Uhrig, U., Sehr, P., Drncova, P., Lewis, J.D., Will, D.W., Cusack, S.
Towards New Anti-Influenza Therapeutics: Structure-Activity Relationships in the Interaction between Heterotrimeric Influenza Polymerase and Pol II C-terminal domain
To Be Published, , pp. - , 0.

Experimental Information:

X-RAY DIFFRACTION

Space Group:

C 1 2 1

Cell Constants:

a = 268.74   b = 147.52   c = 88.54 (Ångstroms)

α = 90.0   β = 96.63   γ = 90.0 (degrees)

Refinement:

The structure was refined using the REFMAC program. The R value is 0.23205 for 77141 reflections in the resolution range 50.0 to 2.8 Ångstroms with Fobs >  0.0 sigma(Fobs) and with I >  0.0 sigma(I)