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NDB ID: 6FKE    PDB ID: 6FKE 


Title:

STRUCTURE OF 3' PHOSPHATASE NEXO (D146N) FROM NEISSERIA BOUND TO PRODUCT DNA HAIRPIN

Molecular Description:

NExo (D146N)/DNA Complex

Deposited:

2018-01-23

Released:

2018-10-31

Structural Keywords:

B DOUBLE HELIX, HAIRPIN LOOP

Nucleic Acid Sequence:

Click to show/hide 1 nucleic acid sequences

Protein Sequence:

Click to show/hide 1 protein sequences

Primary Citation:

Silhan, J., Zhao, Q., Boura, E., Thomson, H., Forster, A., Tang, C.M., Freemont, P.S., Baldwin, G.S.
Structural basis for recognition and repair of the 3'-phosphate by NExo, a base excision DNA repair nuclease from Neisseria meningitidis. 
Nucleic Acids Res., 46, pp. 11980 - 11989, 2018.

Experimental Information:

X-RAY DIFFRACTION

Space Group:

P 43 21 2

Cell Constants:

a = 58.929   b = 58.929   c = 292.591 (Ångstroms)

α = 90.0   β = 90.0   γ = 90.0 (degrees)

Refinement:

The structure was refined using the PHENIX program. The R value is 0.2011 for 29065 reflections in the resolution range 40.075 to 2.151 Ångstroms with Fobs >  1.37 sigma(Fobs) and with I >  0.0 sigma(I)