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NDB ID: 6FQQ    PDB ID: 6FQQ 


Title:

CRYSTAL STRUCTURE OF TALE HOMEOBOX DOMAIN TRANSCRIPTION FACTOR TGIF1 DOUBLE ALANINE MUTANT BOUND TO ITS CONSENSUS DNA

Molecular Description:

Homeobox protein TGIF1/DNA Complex

Structural Keywords:

B DOUBLE HELIX

Nucleic Acid Sequence:

Click to show/hide 1 nucleic acid sequences

Protein Sequence:

Click to show/hide 1 protein sequences

Primary Citation:

Guca, E., Sunol, D., Ruiz, L., Konkol, A., Cordero, J., Torner, C., Aragon, E., Martin-Malpartida, P., Riera, A., Macias, M.J.
TGIF1 homeodomain interacts with Smad MH1 domain and represses TGF-beta signaling. 
Nucleic Acids Res., 46, pp. 9220 - 9235, 2018.

Experimental Information:

X-RAY DIFFRACTION

Space Group:

P 21 21 21

Cell Constants:

a = 60.058   b = 93.016   c = 100.711 (Ångstroms)

α = 90.0   β = 90.0   γ = 90.0 (degrees)

Refinement:

The structure was refined using the phenix.refine program. The R value is 0.217664 for 9236 reflections in the resolution range 45.1103 to 3.25 Ångstroms with Fobs >  0.311475 sigma(Fobs) and with I >  0.0 sigma(I)