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NDB ID: 6FQV    PDB ID: 6FQV 


Title:

2.60A BINARY COMPLEX OF S.AUREUS GYRASE WITH UNCLEAVED DNA

Molecular Description:

DNA gyrase subunit B
DNA gyrase subunit A/DNA Complex

Structural Keywords:

RH DOUBLE HELIX

Nucleic Acid Sequence:

Click to show/hide 1 nucleic acid sequences

Protein Sequence:

Click to show/hide 2 protein sequences

Primary Citation:

Germe, T., Voros, J., Jeannot, F., Taillier, T., Stavenger, R.A., Bacque, E., Maxwell, A., Bax, B.D.
A new class of antibacterials, the imidazopyrazinones, reveal structural transitions involved in DNA gyrase poisoning and mechanisms of resistance. 
Nucleic Acids Res., 46, pp. 4114 - 4128, 2018.

Experimental Information:

X-RAY DIFFRACTION

Space Group:

P 1 21 1

Cell Constants:

a = 93.28   b = 124.64   c = 155.24 (Ångstroms)

α = 90.0   β = 95.65   γ = 90.0 (degrees)

Refinement:

The structure was refined using the BUSTER program. The R value is 0.2014 for 107487 reflections in the resolution range 19.91 to 2.6 Ångstroms with Fobs >  0.0 sigma(Fobs) and with I >  0.0 sigma(I)