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NDB ID: 6G1L    PDB ID: 6G1L 


Title:

MITF/CLEARBOX STRUCTURE

Molecular Description:

Microphthalmia-associated transcription factor/DNA Complex

Deposited:

2018-03-21

Released:

2019-02-06

Structural Keywords:

B DOUBLE HELIX

Nucleic Acid Sequence:

Click to show/hide 1 nucleic acid sequences

Protein Sequence:

Click to show/hide 1 protein sequences

Primary Citation:

Moller, K., Sigurbjornsdottir, S., Arnthorsson, A.O., Pogenberg, V., Dilshat, R., Fock, V., Brynjolfsdottir, S.H., Bindesboll, C., Bessadottir, M., Ogmundsdottir, H.M., Simonsen, A., Larue, L., Wilmanns, M., Thorsson, V., Steingrimsson, E., Ogmundsdottir, M.H.
MITF has a central role in regulating starvation-induced autophagy in melanoma. 
Sci Rep, 9, pp. 1055 - 1055, 2019.

Experimental Information:

X-RAY DIFFRACTION

Space Group:

I 21 21 21

Cell Constants:

a = 44.091   b = 103.858   c = 112.894 (Ångstroms)

α = 90.0   β = 90.0   γ = 90.0 (degrees)

Refinement:

The structure was refined using the PHENIX program. The R value is 0.2164 for 10448 reflections in the resolution range 40.585 to 2.4 Ångstroms with Fobs >  1.35 sigma(Fobs) and with I >  0.0 sigma(I)