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NDB ID: 6GC5    PDB ID: 6GC5 


Title:

MOLECULAR BASIS FOR AU-RICH ELEMENT RECOGNITION AND DIMERIZATION BY THE HUR C-TERMINAL RRM

Molecular Description:

ELAV-like protein 1/RNA Complex

Deposited:

2018-04-17

Released:

2019-01-30

Structural Keywords:

SMALL NA FRAGMENT

Nucleic Acid Sequence:

Click to show/hide 1 nucleic acid sequences

Protein Sequence:

Click to show/hide 1 protein sequences

Primary Citation:

Ripin, N., Boudet, J., Duszczyk, M.M., Hinniger, A., Faller, M., Krepl, M., Gadi, A., Schneider, R.J., Sponer, J., Meisner-Kober, N.C., Allain, F.H.
Molecular basis for AU-rich element recognition and dimerization by the HuR C-terminal RRM. 
Proc. Natl. Acad. Sci. U.S.A., 116, pp. 2935 - 2944, 2019.

Experimental Information:

X-RAY DIFFRACTION

Space Group:

C 1 2 1

Cell Constants:

a = 151.287   b = 40.258   c = 106.496 (Ångstroms)

α = 90.0   β = 132.95   γ = 90.0 (degrees)

Refinement:

The structure was refined using the PHENIX program. The R value is 0.2023 for 35638 reflections in the resolution range 77.946 to 1.9 Ångstroms with Fobs >  1.35 sigma(Fobs) and with I >  0.0 sigma(I)