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NDB ID: 6GMY    PDB ID: 6GMY 


Title:

TC-DNA/RNA DUPLEX

Molecular Description:

Tc-DNA (5'-(*(TCJ)P*(TTK)P*(TCJ)P*(TCS)P*(TCS)P*(TCJ)P*(TTK)P*(TTK)P*(TCY)P*(TCJ))-3')
RNA (5'-R(*GP*UP*AP*AP*GP*CP*CP*GP*AP*G)-3')

Deposited:

2018-05-28

Released:

2018-06-13

Structural Keywords:

A DOUBLE HELIX

Nucleic Acid Sequence:

Click to show/hide 2 nucleic acid sequences

Protein Sequence:

No Protein Sequence Found

Primary Citation:

Istrate, A., Johannsen, S., Istrate, A., Sigel, R.K.O., Leumann, C.J.
NMR solution structure of tricyclo-DNA containing duplexes: insight into enhanced thermal stability and nuclease resistance. 
Nucleic Acids Res., 47, pp. 4872 - 4882, 2019.

Experimental Information:

SOLUTION NMR

Number of Models:

Number of Models: 10 Structures

Sample Details:

0.5 mM tc-DNA/RNA, 50 mM NaCl, 10 mM NaH2PO4, 100% D2O 100% D2O