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NDB ID: 6GPG    PDB ID: 6GPG 


Title:

STRUCTURE OF THE RIG-I SINGLETON-MERTEN SYNDROME VARIANT C268F

Molecular Description:

Probable ATP-dependent RNA helicase DDX58/RNA Complex

Structural Keywords:

A DOUBLE HELIX

Nucleic Acid Sequence:

Click to show/hide 1 nucleic acid sequences

Protein Sequence:

Click to show/hide 1 protein sequences

Primary Citation:

Lassig, C., Lammens, K., Gorenflos Lopez, J.L., Michalski, S., Fettscher, O., Hopfner, K.P.
Unified mechanisms for self-RNA recognition by RIG-I Singleton-Merten syndrome variants. 
Elife, 7, pp. - , 2018.

Experimental Information:

X-RAY DIFFRACTION

Space Group:

P 65 2 2

Cell Constants:

a = 175.62   b = 175.62   c = 109.53 (Ångstroms)

α = 90.0   β = 90.0   γ = 120.0 (degrees)

Refinement:

The structure was refined using the PHENIX program. The R value is 0.2121 for 22649 reflections in the resolution range 46.468 to 2.894 Ångstroms with Fobs >  1.33 sigma(Fobs) and with I >  0.0 sigma(I)