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NDB ID: 6GVT    PDB ID: 6GVT 


Title:

HYBRID STRUCTURE OF THE PRN1 HELIX BUNDLE DOMAIN IN COMPLEX WITH DNA AND 2 ATP MOLECULES

Molecular Description:

functional pRN1 primase/DNA Complex

Deposited:

2018-06-21

Released:

2018-12-26

Structural Keywords:

SMALL NA FRAGMENT

Nucleic Acid Sequence:

Click to show/hide 1 nucleic acid sequences

Protein Sequence:

Click to show/hide 1 protein sequences

Primary Citation:

Boudet, J., Devillier, J.C., Wiegand, T., Salmon, L., Meier, B.H., Lipps, G., Allain, F.H.
A Small Helical Bundle Prepares Primer Synthesis by Binding Two Nucleotides that Enhance Sequence-Specific Recognition of the DNA Template. 
Cell, 176, pp. 154 - 166.e13, 2019.

Experimental Information:

SOLUTION NMR

Number of Models:

Number of Models: 20 Structures

Sample Details:

1.0 mM [U-100% 13C] pRN1 helix bundle domain in complex with DNA and ATP, 1.0 mM DNA (5'-D(*CP*TP*GP*TP*GP*CP*TP*CP*A)-3'), 4.0 mM ADENOSINE-5'-TRIPHOSPHATE, 10 mM magnesium, 100% D2O 100% D2O