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NDB ID: 6GVY    PDB ID: 6GVY 


Title:

MUTANT M16A OF RNA DEPENDENT RNA POLYMERASE 3D FROM FOOT-AND-MOUTH DISEASE VIRUS COMPLEXED WITH AN TEMPLATE -PRIMER RNA

Molecular Description:

Genome polyprotein/RNA Complex

Structural Keywords:

A DOUBLE HELIX

Nucleic Acid Sequence:

Click to show/hide 2 nucleic acid sequences

Protein Sequence:

Click to show/hide 1 protein sequences

Primary Citation:

de la Higuera, I., Ferrer-Orta, C., Moreno, E., de Avila, A.I., Soria, M.E., Singh, K., Caridi, F., Sobrino, F., Sarafianos, S.G., Perales, C., Verdaguer, N., Domingo, E.
Contribution of a multifunctional polymerase region of foot-and-mouth disease virus to lethal mutagenesis. 
J. Virol., , pp. - , 2018.

Experimental Information:

X-RAY DIFFRACTION

Space Group:

P 32 2 1

Cell Constants:

a = 94.073   b = 94.073   c = 99.806 (Ångstroms)

α = 90.0   β = 90.0   γ = 120.0 (degrees)

Refinement:

The structure was refined using the REFMAC program. The R value is 0.23484 for 24864 reflections in the resolution range 42.59 to 2.2 Ångstroms with Fobs >  0.0 sigma(Fobs) and with I >  0.0 sigma(I)