A Portal for Three-dimensional Structural Information about Nucleic Acids
As of 1-Apr-2020 number of released structures: 10687
Search for released structures

NDB ID: 6HMI    PDB ID: 6HMI 


Title:

SOLUTION STRUCTURE OF THE RNA DUPLEX FORMED BY THE 5'-END OF U1SNRNA AND THE 5'-SPLICE SITE OF SMN2 EXON7

Molecular Description:

RNA (5'-R(*AP*UP*AP*CP*(PSU)P*(PSU)P*AP*CP*CP*UP*G)-3')
RNA (5'-R(*GP*GP*AP*GP*UP*AP*AP*GP*UP*CP*U)-3')

Deposited:

2018-09-12

Released:

2019-08-14

Structural Keywords:

A DOUBLE HELIX

Nucleic Acid Sequence:

Click to show/hide 2 nucleic acid sequences

Protein Sequence:

No Protein Sequence Found

Primary Citation:

Campagne, S., Boigner, S., Rudisser, S., Moursy, A., Gillioz, L., Knorlein, A., Hall, J., Ratni, H., Clery, A., Allain, F.H.
Structural basis of a small molecule targeting RNA for a specific splicing correction. 
Nat.Chem.Biol., 15, pp. 1191 - 1198, 2019.

Experimental Information:

SOLUTION NMR

Number of Models:

Number of Models: 20 Structures

Sample Details:

10 mM deuterated MES, 50 mM unlabelled NaCl, 100% D2O 100% D2O