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NDB ID: 6IDE    PDB ID: 6IDE 


Title:

CRYSTAL STRUCTURE OF THE VIBRIO CHOLERA VQMA-LIGAND-DNA COMPLEX PROVIDES MOLECULAR MECHANISMS FOR DRUG DESIGN

Molecular Description:

Transcriptional regulator LuxR family/DNA Complex

Deposited:

2018-09-09

Released:

2019-01-16

Structural Keywords:

RH DOUBLE HELIX

Nucleic Acid Sequence:

Click to show/hide 2 nucleic acid sequences

Protein Sequence:

Click to show/hide 1 protein sequences

Primary Citation:

Wu, H., Li, M., Guo, H., Zhou, H., Li, B., Xu, Q., Xu, C., Yu, F., He, J.
Crystal structure of theVibrio choleraeVqmA-ligand-DNA complex provides insight into ligand-binding mechanisms relevant for drug design. 
J. Biol. Chem., 294, pp. 2580 - 2592, 2019.

Experimental Information:

X-RAY DIFFRACTION

Space Group:

P 21 21 21

Cell Constants:

a = 52.78   b = 108.98   c = 214.32 (Ångstroms)

α = 90.0   β = 90.0   γ = 90.0 (degrees)

Refinement:

The structure was refined using the PHENIX program. The R value is 0.1932 for 43108 reflections in the resolution range 43.326 to 2.51 Ångstroms with Fobs >  1.34 sigma(Fobs) and with I >  0.0 sigma(I)