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NDB ID: 6IFO    PDB ID: 6IFO 


Title:

CRYSTAL STRUCTURE OF ACRIIA2-SPYCAS9-SGRNA TERNARY COMPLEX

Molecular Description:

CRISPR-associated endonuclease Cas9/Csn1
AcrIIA2/RNA Complex

Deposited:

2018-09-20

Released:

2019-01-23

Structural Keywords:

RH DOUBLE HELIX

Nucleic Acid Sequence:

Click to show/hide 1 nucleic acid sequences

Protein Sequence:

Click to show/hide 2 protein sequences

Primary Citation:

Liu, L., Yin, M., Wang, M., Wang, Y.
Phage AcrIIA2 DNA Mimicry: Structural Basis of the CRISPR and Anti-CRISPR Arms Race. 
Mol. Cell, 73, pp. 611 - 620.e3, 2019.

Experimental Information:

X-RAY DIFFRACTION

Space Group:

P 1 21 1

Cell Constants:

a = 106.155   b = 214.567   c = 131.971 (Ångstroms)

α = 90.0   β = 102.89   γ = 90.0 (degrees)

Refinement:

The structure was refined using the PHENIX program. The R value is 0.2247 for 56422 reflections in the resolution range 49.51 to 3.313 Ångstroms with Fobs >  1.38 sigma(Fobs) and with I >  0.0 sigma(I)