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NDB ID: 6JOU    PDB ID: 6JOU     NAKB: 6JOU 


Title:

CRYSTAL STRUCTURE OF THE HUMAN NUCLEOSOME CONTAINING H2A.Z.1 S42R

Molecular Description:

Histone H3.1
Histone H4
Histone H2A.Z
Histone H2B type 1-J/DNA Complex

Deposited:

2019-03-23

Released:

2020-03-25

Structural Keywords:

B DOUBLE HELIX

Nucleic Acid Sequence:

Click to show/hide 1 nucleic acid sequences

Protein Sequence:

Click to show/hide 4 protein sequences

Primary Citation:

Horikoshi, N., Kujirai, T., Sato, K., Kimura, H., Kurumizaka, H.
Structure-based design of an H2A.Z.1 mutant stabilizing a nucleosome in vitro and in vivo. 
Biochem.Biophys.Res.Commun., 515, pp. 719 - 724, 2019.

Experimental Information:

X-RAY DIFFRACTION

Space Group:

P 21 21 21

Cell Constants:

a = 98.955   b = 108.17   c = 169.812 (Ångstroms)

α = 90.0   β = 90.0   γ = 90.0 (degrees)

Refinement:

The structure was refined using the PHENIX program. The R value is 0.2088 for 95610 reflections in the resolution range 49.477 to 2.17 Ångstroms with Fobs >  1.36 sigma(Fobs) and with I >  0.0 sigma(I)