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NDB ID: 6JWE    PDB ID: 6JWE 


Title:

STRUCTURE OF RET G-QUADRUPLEX IN COMPLEX WITH COLCHICINE

Molecular Description:

DNA (5'-D(*GP*GP*GP*GP*CP*GP*GP*GP*GP*CP*GP*GP*GP*GP*CP*GP*GP*GP*GP*T)-3')

Deposited:

2019-04-20

Released:

2020-02-26

Structural Keywords:

QUADRUPLE HELIX

Nucleic Acid Sequence:

Click to show/hide 1 nucleic acid sequences

Protein Sequence:

No Protein Sequence Found

Primary Citation:

Wang, F., Wang, C., Liu, Y., Lan, W., Han, H., Wang, R., Huang, S., Cao, C.
Colchicine selective interaction with oncogene RET G-quadruplex revealed by NMR. 
Chem.Commun.(Camb.), 56, pp. 2099 - 2102, 2020.

Experimental Information:

SOLUTION NMR

Number of Models:

Number of Models: 20 Structures

Sample Details:

0.8 mM RET G4-DNA, 0.96 mM COLCHICINE, 20 mM Potassium Phosphate Monobasic, 80 mM potassium chloride, 90% H2O/10% D2O 90% H2O/10% D2O