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NDB ID: 6K1K    PDB ID: 6K1K 


Title:

HUMAN NUCLEOSOME CORE PARTICLE WITH H2A.X S139E VARIANT

Molecular Description:

Histone H3.1
Histone H4
Histone H2AX
Histone H2B type 1-J/DNA Complex

Deposited:

2019-05-10

Released:

2020-01-15

Structural Keywords:

B DOUBLE HELIX

Nucleic Acid Sequence:

Click to show/hide 2 nucleic acid sequences

Protein Sequence:

Click to show/hide 4 protein sequences

Primary Citation:

Sharma, D., De Falco, L., Padavattan, S., Rao, C., Geifman-Shochat, S., Liu, C.F., Davey, C.A.
PARP1 exhibits enhanced association and catalytic efficiency with gamma H2A.X-nucleosome. 
Nat Commun, 10, pp. 5751 - 5751, 2019.

Experimental Information:

X-RAY DIFFRACTION

Space Group:

P 21 21 21

Cell Constants:

a = 107.95   b = 109.46   c = 183.38 (Ångstroms)

α = 90.0   β = 90.0   γ = 90.0 (degrees)

Refinement:

The structure was refined using the REFMAC program. The R value is 0.2323 for 106763 reflections in the resolution range 93.2 to 2.2 Ångstroms with Fobs >  0.0 sigma(Fobs) and with I >  0.0 sigma(I)