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NDB ID: 6KCS    PDB ID: 6KCS 


Title:

CRYSTAL STRUCTURE OF HIRAN DOMAIN OF HLTF IN COMPLEX WITH DUPLEX DNA

Molecular Description:

Helicase-like transcription factor/DNA Complex

Deposited:

2019-06-28

Released:

2020-06-10

Structural Keywords:

B DOUBLE HELIX

Nucleic Acid Sequence:

Click to show/hide 1 nucleic acid sequences

Protein Sequence:

Click to show/hide 1 protein sequences

Primary Citation:

Hishiki, A., Sato, M., Hashimoto, H.
Structure of HIRAN domain of human HLTF bound to duplex DNA provides structural basis for DNA unwinding to initiate replication fork regression. 
J.Biochem., 167, pp. 597 - 602, 2020.

Experimental Information:

X-RAY DIFFRACTION

Space Group:

P 31 2 1

Cell Constants:

a = 45.363   b = 45.363   c = 125.827 (Ångstroms)

α = 90.0   β = 90.0   γ = 120.0 (degrees)

Refinement:

The structure was refined using the REFMAC program. The R value is 0.23038 for 8806 reflections in the resolution range 19.95 to 2.1 Ångstroms with Fobs >  0.0 sigma(Fobs) and with I >  0.0 sigma(I)