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NDB ID: 6KDO    PDB ID: 6KDO 


Title:

HIV-1 REVERSE TRANSCRIPTASE WITH Q151M/Y115F/F116Y/M184V/F160M:DNA:LAMIVUDINE 5'-TRIPHOSPHATE TERNARY COMPLEX

Molecular Description:

HIV-1 RT p66 subunit/HIV-1 RT p51 subunit/DNA Complex

Deposited:

2019-07-02

Released:

2020-03-04

Structural Keywords:

RH DOUBLE HELIX

Nucleic Acid Sequence:

Click to show/hide 1 nucleic acid sequences

Protein Sequence:

Click to show/hide 2 protein sequences

Primary Citation:

Yasutake, Y., Hattori, S.I., Tamura, N., Matsuda, K., Kohgo, S., Maeda, K., Mitsuya, H.
Structural features in common of HBV and HIV-1 resistance against chirally-distinct nucleoside analogues entecavir and lamivudine. 
Sci Rep, 10, pp. 3021 - 3021, 2020.

Experimental Information:

X-RAY DIFFRACTION

Space Group:

H 3

Cell Constants:

a = 284.239   b = 284.239   c = 95.948 (Ångstroms)

α = 90.0   β = 90.0   γ = 120.0 (degrees)

Refinement:

The structure was refined using the PHENIX program. The R value is 0.1936 for 91591 reflections in the resolution range 48.668 to 2.573 Ångstroms with Fobs >  1.96 sigma(Fobs) and with I >  0.0 sigma(I)