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NDB ID: 6KI6    PDB ID: 6KI6 


Title:

CRYSTAL STRUCTURE OF BCL11A IN COMPLEX WITH GAMMA-GLOBIN -115 HPFH REGION

Molecular Description:

B-cell lymphoma/leukemia 11A/DNA Complex

Deposited:

2019-07-17

Released:

2019-09-11

Structural Keywords:

B DOUBLE HELIX

Nucleic Acid Sequence:

Click to show/hide 2 nucleic acid sequences

Protein Sequence:

Click to show/hide 1 protein sequences

Primary Citation:

Yang, Y., Xu, Z., He, C., Zhang, B., Shi, Y., Li, F.
Structural insights into the recognition of gamma-globin gene promoter by BCL11A. 
Cell Res., , pp. - , 2019.

Experimental Information:

X-RAY DIFFRACTION

Space Group:

P 32 2 1

Cell Constants:

a = 59.555   b = 59.555   c = 213.367 (Ångstroms)

α = 90.0   β = 90.0   γ = 120.0 (degrees)

Refinement:

The structure was refined using the PHENIX program. The R value is 0.2088 for 15839 reflections in the resolution range 37.078 to 2.5 Ångstroms with Fobs >  1.34 sigma(Fobs) and with I >  0.0 sigma(I)