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NDB ID: 6KN4    PDB ID: 6KN4 


Title:

HUMAN PARALLEL STRANDED 7-MER G-QUADRUPLEX COMPLEXED WITH 2 ADRIAMYCIN (DM2) MOLECULES

Molecular Description:

DNA (5'-D(*(T5)P*TP*AP*GP*GP*GP*(T3))-3')

Deposited:

2019-08-03

Released:

2020-03-18

Structural Keywords:

QUADRUPLE HELIX

Nucleic Acid Sequence:

Click to show/hide 1 nucleic acid sequences

Protein Sequence:

No Protein Sequence Found

Primary Citation:

Barthwal, R., Raje, S., Pandav, K.
Structural basis for stabilization of human telomeric G-quadruplex [d-(TTAGGGT)]4by anticancer drug adriamycin. 
J.Biomol.Struct.Dyn., , pp. 1 - 21, 2020.

Experimental Information:

SOLUTION NMR

Number of Models:

Number of Models: 8 Structures

Sample Details:

1.16 mM DNA (5'-D(*(THM)P*TP*AP*GP*GP*GP*(TMP))-3'), 90% H2O/10% D2O 90% H2O/10% D2O