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NDB ID: 6KSF    PDB ID: 6KSF 


Title:

CRYSTAL STRUCTURE OF ALKBH1 BOUND TO 21-MER DNA BULGE

Molecular Description:

Alpha-ketoglutarate-dependent dioxygenase alkB homolog 1/DNA Complex

Deposited:

2019-08-23

Released:

2020-04-08

Structural Keywords:

B DOUBLE HELIX, BULGE

Nucleic Acid Sequence:

Click to show/hide 2 nucleic acid sequences

Protein Sequence:

Click to show/hide 1 protein sequences

Primary Citation:

Zhang, M., Yang, S., Nelakanti, R., Zhao, W., Liu, G., Li, Z., Liu, X., Wu, T., Xiao, A., Li, H.
Mammalian ALKBH1 serves as an N6-mA demethylase of unpairing DNA. 
Cell Res., 30, pp. 197 - 210, 2020.

Experimental Information:

X-RAY DIFFRACTION

Space Group:

P 41 21 2

Cell Constants:

a = 67.482   b = 67.482   c = 263.641 (Ångstroms)

α = 90.0   β = 90.0   γ = 90.0 (degrees)

Refinement:

The structure was refined using the PHENIX program. The R value is 0.2302 for 24541 reflections in the resolution range 32.888 to 2.4 Ångstroms with Fobs >  1.37 sigma(Fobs) and with I >  0.0 sigma(I)