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NDB ID: 6L92    PDB ID: 6L92 


Title:

A BASKET TYPE G-QUADRUPLEX IN WNT DNA PROMOTER

Molecular Description:

DNA (5'-D(*GP*GP*GP*CP*CP*AP*CP*CP*GP*GP*GP*CP*AP*GP*TP*GP*GP*GP*CP*GP*GP*G)-3')

Deposited:

2019-11-08

Released:

2019-12-11

Structural Keywords:

QUADRUPLE HELIX

Nucleic Acid Sequence:

Click to show/hide 1 nucleic acid sequences

Protein Sequence:

No Protein Sequence Found

Primary Citation:

Wang, Z.F., Li, M.H., Chu, I.T., Winnerdy, F.R., Phan, A.T., Chang, T.C.
Cytosine epigenetic modification modulates the formation of an unprecedented G4 structure in the WNT1 promoter. 
Nucleic Acids Res., 48, pp. 1120 - 1130, 2020.

Experimental Information:

SOLUTION NMR

Number of Models:

Number of Models: 10 Structures

Sample Details:

1 mM DNA (5'-D(*GP*GP*GP*CP*CP*AP*CP*CP*GP*GP*GP*CP*AP*GP*TP*GP*GP*GP*CP*GP*GP*G)-3'), 90% H2O/10% D2O 90% H2O/10% D2O