## NDB ID: 6L9H PDB ID: 6L9H

### Title:

THE HUMAN TELOMERIC NUCLEOSOME DISPLAYS DISTINCT STRUCTURAL AND DYNAMIC PROPERTIES

### Molecular Description:

Histone H3.1

Histone H4

Histone H2A type 1-B/E

Histone H2B type 1-K/DNA Complex

### Deposited:

2019-11-10

### Released:

2020-04-22

### Structural Keywords:

B DOUBLE HELIX

### Nucleic Acid Sequence:

Click to show/hide 2 nucleic acid sequences

Chain I

(DA)(DT)(DC)(DT)(DT)(DA)(DG)(DG)(DG)(DT)(DT)(DA)(DG)(DG)(DG)(DT)(DT)(DA)(DG)(DG) (DG)(DT)(

DT)(DA)(DG)(DG)(DG)(DT)(DT)(DA)(DG)(DG)(DG)(DT)(DT)(DA)(DG)(DG)(DG)(DT) (DT)(DA)(DG)(DG)(D

G)(DT)(DT)(DA)(DG)(DG)(DG)(DT)(DT)(DA)(DG)(DG)(DG)(DT)(DT)(DA) (DG)(DG)(DG)(DT)(DT)(DA)(DG

)(DG)(DG)(DT)(DT)(DA)(DG)(DG)(DG)(DT)(DT)(DA)(DG)(DG) (DG)(DT)(DT)(DA)(DG)(DG)(DG)(DT)(DT)

(DA)(DG)(DG)(DG)(DT)(DT)(DA)(DG)(DG)(DG)(DT) (DT)(DA)(DG)(DG)(DG)(DT)(DT)(DA)(DG)(DG)(DG)(

DT)(DT)(DA)(DG)(DG)(DG)(DT)(DT)(DA) (DG)(DG)(DG)(DT)(DT)(DA)(DG)(DG)(DG)(DT)(DT)(DA)(DG)(D

G)(DG)(DT)(DT)(DA)(DG)(DG) (DG)(DT)(DG)(DA)(DT)

Chain J

(DA)(DT)(DC)(DA)(DC)(DC)(DC)(DT)(DA)(DA)(DC)(DC)(DC)(DT)(DA)(DA)(DC)(DC)(DC)(DT) (DA)(DA)(

DC)(DC)(DC)(DT)(DA)(DA)(DC)(DC)(DC)(DT)(DA)(DA)(DC)(DC)(DC)(DT)(DA)(DA) (DC)(DC)(DC)(DT)(D

A)(DA)(DC)(DC)(DC)(DT)(DA)(DA)(DC)(DC)(DC)(DT)(DA)(DA)(DC)(DC) (DC)(DT)(DA)(DA)(DC)(DC)(DC

)(DT)(DA)(DA)(DC)(DC)(DC)(DT)(DA)(DA)(DC)(DC)(DC)(DT) (DA)(DA)(DC)(DC)(DC)(DT)(DA)(DA)(DC)

(DC)(DC)(DT)(DA)(DA)(DC)(DC)(DC)(DT)(DA)(DA) (DC)(DC)(DC)(DT)(DA)(DA)(DC)(DC)(DC)(DT)(DA)(

DA)(DC)(DC)(DC)(DT)(DA)(DA)(DC)(DC) (DC)(DT)(DA)(DA)(DC)(DC)(DC)(DT)(DA)(DA)(DC)(DC)(DC)(D

T)(DA)(DA)(DC)(DC)(DC)(DT) (DA)(DA)(DG)(DA)(DT)

### Protein Sequence:

Click to show/hide 4 protein sequences

Chain A,E

RYRPGTVALREIRRYQKSTELLIRKLPFQRLVREIAQDFKTDLRFQSSAVMALQEACEAYLVGLFEDTNLCAIHAKRVTI MPKDIQLAR

RIRGERA

Chain C,G

AKTRSSRAGLQFPVGRVHRLLRKGNYSERVGAGAPVYLAAVLEYLTAEILELAGNAARDNKKTRIIPRHLQLAIRNDEEL NKLLGRVTI

AQGGVLPNIQAVLLPK

Chain B,F

KRHRKVLRDNIQGITKPAIRRLARRGGVKRISGLIYEETRGVLKVFLENVIRDAVTYTEHAKRKTVTAMDVVYALKRQGR TLYGFGG

Chain D,H

RSRKESYSVYVYKVLKQVHPDTGISSKAMGIMNSFVNDIFERIAGEASRLAHYNKRSTITSREIQTAVRLLLPGELAKHA VSEGTKAVT

KYTSAK

### Primary Citation:

Soman, A., Liew, C.W., Teo, H.L., Berezhnoy, N., Olieric, V., Korolev, N., Rhodes, D., Nordenskiold, L.

Crystal Structure and Solution Properties of the Telomeric Nucleosome

*Biorxiv*, , pp. - , 2019.

### Experimental Information:

X-RAY DIFFRACTION

### Space Group:

P 21 21 21

### Cell Constants:

a = 106.455 b = 109.388 c = 176.376 (Ångstroms)

α = 90.0 β = 90.0 γ = 90.0 (degrees)

### Refinement:

The structure was refined using the BUSTER program.
The R value is 0.2384 for 33177 reflections in
the resolution range 46.0 to 2.6 Ångstroms
with Fobs > 0.0 sigma(Fobs) and with I > 0.0 sigma(I)