## NDB ID: 6LA2 PDB ID: 6LA2

### Title:

343 BP DI-NUCLEOSOME HARBORING COHESIVE DNA TERMINI ASSEMBLED WITH LINKER HISTONE H1.0

### Molecular Description:

Histone H3.1

Histone H4

Histone H2AX

Histone H2B type 1-J/DNA Complex

### Deposited:

2019-11-11

### Released:

2021-02-17

### Structural Keywords:

B DOUBLE HELIX

### Nucleic Acid Sequence:

Click to show/hide 2 nucleic acid sequences

Chain I,c

(DC)(DG)(DC)(DT)(DG)(DA)(DA)(DA)(DA)(DA)(DA)(DA)(DA)(DC)(DG)(DC)(DA)(DT)(DC)(DC) (DC)(DG)(

DG)(DT)(DG)(DC)(DC)(DG)(DA)(DG)(DG)(DC)(DC)(DG)(DC)(DT)(DC)(DA)(DA)(DT) (DT)(DG)(DG)(DT)(D

C)(DG)(DT)(DA)(DG)(DA)(DC)(DA)(DG)(DC)(DT)(DC)(DT)(DA)(DG)(DC) (DA)(DC)(DC)(DG)(DC)(DT)(DT

)(DA)(DA)(DA)(DC)(DG)(DC)(DA)(DC)(DG)(DT)(DA)(DC)(DG) (DC)(DG)(DC)(DT)(DG)(DT)(DC)(DT)(DA)

(DC)(DC)(DG)(DC)(DG)(DT)(DT)(DT)(DT)(DA)(DA) (DC)(DC)(DG)(DC)(DC)(DA)(DC)(DT)(DA)(DG)(DA)(

DA)(DG)(DC)(DG)(DC)(DT)(DT)(DA)(DC) (DT)(DA)(DG)(DT)(DC)(DT)(DC)(DC)(DA)(DG)(DG)(DC)(DA)(D

C)(DG)(DT)(DG)(DT)(DG)(DA) (DG)(DA)(DC)(DC)(DG)(DG)(DC)(DA)(DC)(DA)(DT)(DG)(DA)(DA)(DA)(DA

)(DA)(DA)(DA)(DA) (DA)(DA)(DG)(DC)(DA)(DT)(DG)(DC)(DT)(DC)(DG)(DA)(DG)(DT)(DA)(DT)(DG)(DA)

(DA)(DA) (DA)(DA)(DA)(DA)(DA)(DA)(DA)(DC)(DG)(DC)(DA)(DT)(DC)(DC)(DC)(DG)(DG)(DT)(DG)(DC)

(DC)(DG)(DA)(DG)(DG)(DC)(DC)(DG)(DC)(DT)(DC)(DA)(DA)(DT)(DT)(DG)(DG)(DT)(DC)(DG) (DT)(DA)(

DG)(DA)(DC)(DA)(DG)(DC)(DT)(DC)(DT)(DA)(DG)(DC)(DA)(DC)(DC)(DG)(DC)(DT) (DT)(DA)(DA)(DA)(D

C)(DG)(DC)(DA)(DC)(DG)(DT)(DA)(DC)(DG)(DC)(DG)(DC)(DT)(DG)(DT) (DC)(DT)(DA)(DC)(DC)(DG)(DC

)(DG)(DT)(DT)(DT)(DT)(DA)(DA)(DC)(DC)(DG)(DC)(DC)(DA) (DC)(DT)(DA)(DG)(DA)(DA)(DG)(DC)(DG)

(DC)(DT)(DT)(DA)(DC)(DT)(DA)(DG)(DT)(DC)(DT) (DC)(DC)(DA)(DG)(DG)(DC)(DA)(DC)(DG)(DT)(DG)(

DT)(DG)(DA)(DG)(DA)(DC)(DC)(DG)(DG) (DC)(DA)(DC)(DA)(DT)(DG)(DA)(DA)(DA)(DA)(DA)(DA)(DA)(D

A)(DC)(DA)(DG)(DC)(DG)(DG) (DT)(DA)(DC)

Chain J,d

(DC)(DG)(DC)(DT)(DG)(DT)(DT)(DT)(DT)(DT)(DT)(DT)(DT)(DC)(DA)(DT)(DG)(DT)(DG)(DC) (DC)(DG)(

DG)(DT)(DC)(DT)(DC)(DA)(DC)(DA)(DC)(DG)(DT)(DG)(DC)(DC)(DT)(DG)(DG)(DA) (DG)(DA)(DC)(DT)(D

A)(DG)(DT)(DA)(DA)(DG)(DC)(DG)(DC)(DT)(DT)(DC)(DT)(DA)(DG)(DT) (DG)(DG)(DC)(DG)(DG)(DT)(DT

)(DA)(DA)(DA)(DA)(DC)(DG)(DC)(DG)(DG)(DT)(DA)(DG)(DA) (DC)(DA)(DG)(DC)(DG)(DC)(DG)(DT)(DA)

(DC)(DG)(DT)(DG)(DC)(DG)(DT)(DT)(DT)(DA)(DA) (DG)(DC)(DG)(DG)(DT)(DG)(DC)(DT)(DA)(DG)(DA)(

DG)(DC)(DT)(DG)(DT)(DC)(DT)(DA)(DC) (DG)(DA)(DC)(DC)(DA)(DA)(DT)(DT)(DG)(DA)(DG)(DC)(DG)(D

G)(DC)(DC)(DT)(DC)(DG)(DG) (DC)(DA)(DC)(DC)(DG)(DG)(DG)(DA)(DT)(DG)(DC)(DG)(DT)(DT)(DT)(DT

)(DT)(DT)(DT)(DT) (DT)(DT)(DC)(DA)(DT)(DA)(DC)(DT)(DC)(DG)(DA)(DG)(DC)(DA)(DT)(DG)(DC)(DT)

(DT)(DT) (DT)(DT)(DT)(DT)(DT)(DT)(DT)(DC)(DA)(DT)(DG)(DT)(DG)(DC)(DC)(DG)(DG)(DT)(DC)(DT)

(DC)(DA)(DC)(DA)(DC)(DG)(DT)(DG)(DC)(DC)(DT)(DG)(DG)(DA)(DG)(DA)(DC)(DT)(DA)(DG) (DT)(DA)(

DA)(DG)(DC)(DG)(DC)(DT)(DT)(DC)(DT)(DA)(DG)(DT)(DG)(DG)(DC)(DG)(DG)(DT) (DT)(DA)(DA)(DA)(D

A)(DC)(DG)(DC)(DG)(DG)(DT)(DA)(DG)(DA)(DC)(DA)(DG)(DC)(DG)(DC) (DG)(DT)(DA)(DC)(DG)(DT)(DG

)(DC)(DG)(DT)(DT)(DT)(DA)(DA)(DG)(DC)(DG)(DG)(DT)(DG) (DC)(DT)(DA)(DG)(DA)(DG)(DC)(DT)(DG)

(DT)(DC)(DT)(DA)(DC)(DG)(DA)(DC)(DC)(DA)(DA) (DT)(DT)(DG)(DA)(DG)(DC)(DG)(DG)(DC)(DC)(DT)(

DC)(DG)(DG)(DC)(DA)(DC)(DC)(DG)(DG) (DG)(DA)(DT)(DG)(DC)(DG)(DT)(DT)(DT)(DT)(DT)(DT)(DT)(D

T)(DC)(DA)(DG)(DC)(DG)(DG) (DT)(DA)(DC)

### Protein Sequence:

Click to show/hide 5 protein sequences

Chain e,i,A,E,K,O,U,Y

MARTKQTARKSTGGKAPRKQLATKAARKSAPATGGVKKPHRYRPGTVALREIRRYQKSTELLIRKLPFQRLVREIAQDFK TDLRFQSSA

VMALQEACEAYLVGLFEDTNLCAIHAKRVTIMPKDIQLARRIRGERA

Chain g,k,C,G,M,Q,W,a

MSGRGKQGGKARAKAKTRSSRAGLQFPVGRVHRLLRKGNYSERVGAGAPVYLAAVLEYLTAEILELAGNAARDNKKTRII PRHLQLAIR

NDEELNKLLGRVTIAQGGVLPNIQAVLLPKKTESHHKAKGK

Chain f,j,B,F,L,P,V,Z

MSGRGKGGKGLGKGGAKRHRKVLRDNIQGITKPAIRRLARRGGVKRISGLIYEETRGVLKVFLENVIRDAVTYTEHAKRK TVTAMDVVY

ALKRQGRTLYGFGG

Chain h,l,D,H,N,R,X,b

MPEPAKSAPAPKKGSKKAVTKAQKKDGKKRKRSRKESYSIYVYKVLKQVHPDTGISSKAMGIMNSFVNDIFERIAGEASR LAHYNKRST

ITSREIQTAVRLLLPGELAKHAVSEGTKAVTKYTSAK

Chain S,T

MTENSTSAPAAKPKRAKASKKSTDHPKYSDMIVAAIQAEKNRAGSSRQSIQKYIKSHYKVGENADSQIKLSIKRLVTTGV LKQTKGVGA

SGSFRLAKSDEPKKSVAFKKTKKEIKKVATPKKASKPKKAASKAPTKKPKATPVKKAKKKLAATPKKAKKP KTVKAKPVKASKPKKAKP

VKPKAKSSAKRAGKKK

### Primary Citation:

Sharma, D., Davey, C.A., Adhireksan, Z.

Dinucleosome 338 bp with linker histone H1.X

*To Be Published*, , pp. - , 0.

### Experimental Information:

X-RAY DIFFRACTION

### Space Group:

P 1 21 1

### Cell Constants:

a = 107.755 b = 205.904 c = 237.677 (Ångstroms)

α = 90.0 β = 97.19 γ = 90.0 (degrees)

### Refinement:

The structure was refined using the REFMAC program.
The R value is 0.2005 for 91832 reflections in
the resolution range 49.35 to 3.89 Ångstroms
with Fobs > 0.0 sigma(Fobs) and with I > 0.0 sigma(I)