## NDB ID: 6LAB PDB ID: 6LAB

### Title:

169 BP NUCLEOSOME, HARBORING COHESIVE DNA TERMINI, ASSEMBLED WITH LINKER HISTONE H1.0

### Molecular Description:

Histone H3.1

Histone H4

Histone H2AX

Histone H2B type 1-J/DNA Complex

### Deposited:

2019-11-12

### Released:

2021-02-17

### Structural Keywords:

B DOUBLE HELIX

### Nucleic Acid Sequence:

Click to show/hide 2 nucleic acid sequences

Chain I,S

(DG)(DC)(DT)(DT)(DT)(DT)(DT)(DT)(DT)(DT)(DT)(DT)(DC)(DA)(DC)(DA)(DA)(DT)(DC)(DC) (DC)(DG)(

DG)(DT)(DG)(DC)(DC)(DG)(DA)(DG)(DG)(DC)(DC)(DG)(DC)(DT)(DC)(DA)(DA)(DT) (DT)(DG)(DG)(DT)(D

C)(DG)(DT)(DA)(DG)(DA)(DC)(DA)(DG)(DC)(DT)(DC)(DT)(DA)(DG)(DC) (DA)(DC)(DC)(DG)(DC)(DT)(DT

)(DA)(DA)(DA)(DC)(DG)(DC)(DA)(DC)(DG)(DT)(DA)(DC)(DG) (DG)(DA)(DA)(DT)(DC)(DC)(DG)(DT)(DA)

(DC)(DG)(DT)(DG)(DC)(DG)(DT)(DT)(DT)(DA)(DA) (DG)(DC)(DG)(DG)(DT)(DG)(DC)(DT)(DA)(DG)(DA)(

DG)(DC)(DT)(DG)(DT)(DC)(DT)(DA)(DC) (DG)(DA)(DC)(DC)(DA)(DA)(DT)(DT)(DG)(DA)(DG)(DC)(DG)(D

G)(DC)(DC)(DT)(DC)(DG)(DG) (DC)(DA)(DC)(DC)(DG)(DG)(DG)(DA)(DT)(DT)(DG)(DT)(DG)(DA)(DA)(DA

)(DA)(DA)(DA)(DA) (DA)(DA)(DA)(DG)(DC)(DT)(DG)(DC)(DA)

Chain J,T

(DG)(DC)(DT)(DT)(DT)(DT)(DT)(DT)(DT)(DT)(DT)(DT)(DC)(DA)(DC)(DA)(DA)(DT)(DC)(DC) (DC)(DG)(

DG)(DT)(DG)(DC)(DC)(DG)(DA)(DG)(DG)(DC)(DC)(DG)(DC)(DT)(DC)(DA)(DA)(DT) (DT)(DG)(DG)(DT)(D

C)(DG)(DT)(DA)(DG)(DA)(DC)(DA)(DG)(DC)(DT)(DC)(DT)(DA)(DG)(DC) (DA)(DC)(DC)(DG)(DC)(DT)(DT

)(DA)(DA)(DA)(DC)(DG)(DC)(DA)(DC)(DG)(DT)(DA)(DC)(DG) (DG)(DA)(DT)(DT)(DC)(DC)(DG)(DT)(DA)

(DC)(DG)(DT)(DG)(DC)(DG)(DT)(DT)(DT)(DA)(DA) (DG)(DC)(DG)(DG)(DT)(DG)(DC)(DT)(DA)(DG)(DA)(

DG)(DC)(DT)(DG)(DT)(DC)(DT)(DA)(DC) (DG)(DA)(DC)(DC)(DA)(DA)(DT)(DT)(DG)(DA)(DG)(DC)(DG)(D

G)(DC)(DC)(DT)(DC)(DG)(DG) (DC)(DA)(DC)(DC)(DG)(DG)(DG)(DA)(DT)(DT)(DG)(DT)(DG)(DA)(DA)(DA

)(DA)(DA)(DA)(DA) (DA)(DA)(DA)(DG)(DC)(DT)(DG)(DC)(DA)

### Protein Sequence:

Click to show/hide 5 protein sequences

Chain A,E,K,O

MARTKQTARKSTGGKAPRKQLATKAARKSAPATGGVKKPHRYRPGTVALREIRRYQKSTELLIRKLPFQRLVREIAQDFK TDLRFQSSA

VMALQEACEAYLVGLFEDTNLCAIHAKRVTIMPKDIQLARRIRGERA

Chain C,G,M,Q

MSGRGKQGGKARAKAKTRSSRAGLQFPVGRVHRLLRKGNYSERVGAGAPVYLAAVLEYLTAEILELAGNAARDNKKTRII PRHLQLAIR

NDEELNKLLGRVTIAQGGVLPNIQAVLLPKKTESHHKAKGK

Chain B,F,L,P

MSGRGKGGKGLGKGGAKRHRKVLRDNIQGITKPAIRRLARRGGVKRISGLIYEETRGVLKVFLENVIRDAVTYTEHAKRK TVTAMDVVY

ALKRQGRTLYGFGG

Chain D,H,N,R

MPEPAKSAPAPKKGSKKAVTKAQKKDGKKRKRSRKESYSIYVYKVLKQVHPDTGISSKAMGIMNSFVNDIFERIAGEASR LAHYNKRST

ITSREIQTAVRLLLPGELAKHAVSEGTKAVTKYTSAK

Chain U,V

MTENSTSAPAAKPKRAKASKKSTDHPKYSDMIVAAIQAEKNRAGSSRQSIQKYIKSHYKVGENADSQIKLSIKRLVTTGV LKQTKGVGA

SGSFRLAKSDEPKKSVAFKKTKKEIKKVATPKKASKPKKAASKAPTKKPKATPVKKAKKKLAATPKKAKKP KTVKAKPVKASKPKKAKP

VKPKAKSSAKRAGKKK

### Primary Citation:

Sharma, D., Davey, C.A., Adhireksan, Z.

Nucleosome 169 bp with linker histone H1.0

*To Be Published*, , pp. - , 0.

### Experimental Information:

X-RAY DIFFRACTION

### Space Group:

P 1 21 1

### Cell Constants:

a = 104.799 b = 102.76 c = 218.05 (Ångstroms)

α = 90.0 β = 97.4 γ = 90.0 (degrees)

### Refinement:

The structure was refined using the REFMAC program.
The R value is 0.2097 for 74093 reflections in
the resolution range 216.23 to 3.2 Ångstroms
with Fobs > 0.0 sigma(Fobs) and with I > 0.0 sigma(I)