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NDB ID: 6LAE    PDB ID: 6LAE 


Title:

CRYSTAL STRUCTURE OF THE DNA-BINDING DOMAIN OF HUMAN XPA IN COMPLEX WITH DNA

Molecular Description:

DNA repair protein complementing XP-A cells/DNA Complex

Deposited:

2019-11-12

Released:

2020-02-26

Structural Keywords:

B DOUBLE HELIX

Nucleic Acid Sequence:

Click to show/hide 2 nucleic acid sequences

Protein Sequence:

Click to show/hide 1 protein sequences

Primary Citation:

Lian, F.M., Yang, X., Jiang, Y.L., Yang, F., Li, C., Yang, W., Qian, C.
New structural insights into the recognition of undamaged splayed-arm DNA with a single pair of non-complementary nucleotides by human nucleotide excision repair protein XPA. 
Int.J.Biol.Macromol., 148, pp. 466 - 474, 2020.

Experimental Information:

X-RAY DIFFRACTION

Space Group:

P 31

Cell Constants:

a = 69.112   b = 69.112   c = 63.938 (Ångstroms)

α = 90.0   β = 90.0   γ = 120.0 (degrees)

Refinement:

The structure was refined using the REFMAC program. The R value is 0.2198 for 7335 reflections in the resolution range 43.7 to 2.81 Ångstroms with Fobs >  0.0 sigma(Fobs) and with I >  0.0 sigma(I)