## NDB ID: 6LER PDB ID: 6LER

### Title:

169 BP NUCLEOSOME HARBORING NON-IDENTICAL COHESIVE DNA TERMINI.

### Molecular Description:

Histone H3.1

Histone H4

Histone H2AX

Histone H2B type 1-J/DNA Complex

### Deposited:

2019-11-26

### Released:

2021-03-03

### Structural Keywords:

B DOUBLE HELIX

### Nucleic Acid Sequence:

Click to show/hide 2 nucleic acid sequences

Chain S,J

(DC)(DG)(DT)(DT)(DT)(DT)(DT)(DT)(DT)(DT)(DT)(DT)(DG)(DC)(DA)(DT)(DG)(DT)(DG)(DC) (DC)(DG)(

DG)(DT)(DC)(DT)(DC)(DA)(DC)(DA)(DC)(DG)(DT)(DG)(DC)(DC)(DT)(DG)(DG)(DA) (DG)(DA)(DC)(DT)(D

A)(DG)(DT)(DA)(DA)(DG)(DC)(DG)(DC)(DT)(DT)(DC)(DT)(DA)(DG)(DT) (DG)(DG)(DC)(DG)(DG)(DT)(DT

)(DA)(DA)(DA)(DA)(DC)(DG)(DC)(DG)(DG)(DT)(DA)(DG)(DA) (DC)(DA)(DG)(DC)(DG)(DC)(DG)(DT)(DA)

(DC)(DG)(DT)(DG)(DC)(DG)(DT)(DT)(DT)(DA)(DA) (DG)(DC)(DG)(DG)(DT)(DG)(DC)(DT)(DA)(DG)(DA)(

DG)(DC)(DT)(DG)(DT)(DC)(DT)(DA)(DC) (DG)(DA)(DC)(DC)(DA)(DA)(DT)(DT)(DG)(DA)(DG)(DC)(DG)(D

G)(DC)(DC)(DT)(DC)(DG)(DG) (DC)(DA)(DC)(DC)(DG)(DG)(DG)(DA)(DT)(DG)(DC)(DT)(DG)(DT)(DT)(DT

)(DT)(DT)(DT)(DT) (DT)(DT)(DT)(DG)(DG)(DG)(DT)(DA)(DC)

Chain T,I

(DC)(DC)(DA)(DA)(DA)(DA)(DA)(DA)(DA)(DA)(DA)(DA)(DC)(DA)(DG)(DC)(DA)(DT)(DC)(DC) (DC)(DG)(

DG)(DT)(DG)(DC)(DC)(DG)(DA)(DG)(DG)(DC)(DC)(DG)(DC)(DT)(DC)(DA)(DA)(DT) (DT)(DG)(DG)(DT)(D

C)(DG)(DT)(DA)(DG)(DA)(DC)(DA)(DG)(DC)(DT)(DC)(DT)(DA)(DG)(DC) (DA)(DC)(DC)(DG)(DC)(DT)(DT

)(DA)(DA)(DA)(DC)(DG)(DC)(DA)(DC)(DG)(DT)(DA)(DC)(DG) (DC)(DG)(DC)(DT)(DG)(DT)(DC)(DT)(DA)

(DC)(DC)(DG)(DC)(DG)(DT)(DT)(DT)(DT)(DA)(DA) (DC)(DC)(DG)(DC)(DC)(DA)(DC)(DT)(DA)(DG)(DA)(

DA)(DG)(DC)(DG)(DC)(DT)(DT)(DA)(DC) (DT)(DA)(DG)(DT)(DC)(DT)(DC)(DC)(DA)(DG)(DG)(DC)(DA)(D

C)(DG)(DT)(DG)(DT)(DG)(DA) (DG)(DA)(DC)(DC)(DG)(DG)(DC)(DA)(DC)(DA)(DT)(DG)(DC)(DA)(DA)(DA

)(DA)(DA)(DA)(DA) (DA)(DA)(DA)(DC)(DG)(DA)(DG)(DC)(DT)

### Protein Sequence:

Click to show/hide 4 protein sequences

Chain K,O,A,E

MARTKQTARKSTGGKAPRKQLATKAARKSAPATGGVKKPHRYRPGTVALREIRRYQKSTELLIRKLPFQRLVREIAQDFK TDLRFQSSA

VMALQEACEAYLVGLFEDTNLCAIHAKRVTIMPKDIQLARRIRGERA

Chain M,Q,C,G

MSGRGKQGGKARAKAKTRSSRAGLQFPVGRVHRLLRKGNYSERVGAGAPVYLAAVLEYLTAEILELAGNAARDNKKTRII PRHLQLAIR

NDEELNKLLGRVTIAQGGVLPNIQAVLLPKKTESHHKAKGK

Chain L,P,B,F

MSGRGKGGKGLGKGGAKRHRKVLRDNIQGITKPAIRRLARRGGVKRISGLIYEETRGVLKVFLENVIRDAVTYTEHAKRK TVTAMDVVY

ALKRQGRTLYGFGG

Chain N,R,D,H

MPEPAKSAPAPKKGSKKAVTKAQKKDGKKRKRSRKESYSIYVYKVLKQVHPDTGISSKAMGIMNSFVNDIFERIAGEASR LAHYNKRST

ITSREIQTAVRLLLPGELAKHAVSEGTKAVTKYTSAK

### Primary Citation:

Sharma, D., Davey, C.A., Adhireksan, Z.

169 bp nucleosome harboring non-palindromic DNA with cohesive ends.

*To Be Published*, , pp. - , 0.

### Experimental Information:

X-RAY DIFFRACTION

### Space Group:

P 1

### Cell Constants:

a = 107.338 b = 116.545 c = 117.9 (Ångstroms)

α = 61.5 β = 82.77 γ = 64.23 (degrees)

### Refinement:

The structure was refined using the REFMAC program.
The R value is 0.2094 for 86975 reflections in
the resolution range 48.12 to 3.0 Ångstroms
with Fobs > 0.0 sigma(Fobs) and with I > 0.0 sigma(I)