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NDB ID: 6LU0    PDB ID: 6LU0 


Title:

CRYSTAL STRUCTURE OF CAS12I2 TERNARY COMPLEX WITH 12 NT SPACER

Molecular Description:

Cas12i2/DNA/RNA Complex

Deposited:

2020-01-24

Released:

2020-10-28

Structural Keywords:

RH DOUBLE HELIX

Nucleic Acid Sequence:

Click to show/hide 3 nucleic acid sequences

Protein Sequence:

Click to show/hide 1 protein sequences

Primary Citation:

Huang, X., Sun, W., Cheng, Z., Chen, M., Li, X., Wang, J., Sheng, G., Gong, W., Wang, Y.
Structural basis for two metal-ion catalysis of DNA cleavage by Cas12i2. 
Nat Commun, 11, pp. 5241 - 5241, 2020.

Experimental Information:

X-RAY DIFFRACTION

Space Group:

C 2 2 21

Cell Constants:

a = 93.553   b = 122.672   c = 284.712 (Ångstroms)

α = 90.0   β = 90.0   γ = 90.0 (degrees)

Refinement:

The structure was refined using the PHENIX program. The R value is 0.2082 for 26260 reflections in the resolution range 29.56 to 3.22 Ångstroms with Fobs >  1.35 sigma(Fobs) and with I >  0.0 sigma(I)