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NDB ID: 6M7O    PDB ID: 6M7O 


Title:

HUMAN DNA POLYMERASE ETA TERNARY COMPLEX WITH MN2+ AND DTMPNPP OPPOSITING CDA

Molecular Description:

DNA polymerase eta/DNA Complex

Structural Keywords:

B DOUBLE HELIX

Nucleic Acid Sequence:

Click to show/hide 2 nucleic acid sequences

Protein Sequence:

Click to show/hide 1 protein sequences

Primary Citation:

Weng, P., Gao, Y., Gregory, M.T., Wang, P., Wang, Y., Yang, W.
Bypassing a 8,5'-cyclo-2'-deoxyadenosine lesion by human DNA polymerase eta at atomic resolution
Proc.Natl.Acad.Sci.Usa, , pp. - , 2018.

Experimental Information:

X-RAY DIFFRACTION

Space Group:

P 61

Cell Constants:

a = 98.9   b = 98.9   c = 81.06 (Ångstroms)

α = 90.0   β = 90.0   γ = 120.0 (degrees)

Refinement:

The structure was refined using the PHENIX program. The R value is 0.2332 for 9105 reflections in the resolution range 29.437 to 3.0 Ångstroms with Fobs >  1.23 sigma(Fobs) and with I >  0.0 sigma(I)