A Portal for Three-dimensional Structural Information about Nucleic Acids
As of 15-Mar-2023 number of released structures: 12686
Search for released structures

NDB ID: 6M7T    PDB ID: 6M7T     NAKB(beta): 6M7T 


Title:

HUMAN DNA POLYMERASE ETA IN A NON-PRODUCTIVE TERNARY COMPLEX WITH CA2+ AND DTTP OPPOSITING CDA

Molecular Description:

DNA polymerase eta/DNA Complex

Deposited:

2018-08-21

Released:

2018-09-12

Structural Keywords:

B DOUBLE HELIX

Nucleic Acid Sequence:

Click to show/hide 2 nucleic acid sequences

Protein Sequence:

Click to show/hide 1 protein sequences

Primary Citation:

Weng, P.J., Gao, Y., Gregory, M.T., Wang, P., Wang, Y., Yang, W.
Bypassing a 8,5'-cyclo-2'-deoxyadenosine lesion by human DNA polymerase eta at atomic resolution. 
Proc. Natl. Acad. Sci. U.S.A., 115, pp. 10660 - 10665, 2018.

Experimental Information:

X-RAY DIFFRACTION

Space Group:

P 21 21 21

Cell Constants:

a = 65.65   b = 80.93   c = 140.38 (Ångstroms)

α = 90.0   β = 90.0   γ = 90.0 (degrees)

Refinement:

The structure was refined using the PHENIX program. The R value is 0.2221 for 19001 reflections in the resolution range 29.734 to 2.8 Ångstroms with Fobs >  0.98 sigma(Fobs) and with I >  0.0 sigma(I)