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NDB ID: 6MCE    PDB ID: 6MCE 


Title:

SOLUTION STRUCTURE OF HIV-1 TAR WITH TAT RNA BINDING DOMAIN

Molecular Description:

Protein Tat/RNA Complex

Structural Keywords:

Nucleic Acid Sequence:

Click to show/hide 1 nucleic acid sequences

Protein Sequence:

Click to show/hide 1 protein sequences

Primary Citation:

Pham, V.V., Salguero, C., Khan, S.N., Meagher, J.L., Brown, W.C., Humbert, N., de Rocquigny, H., Smith, J.L., D'Souza, V.M.
HIV-1 Tat interactions with cellular 7SK and viral TAR RNAs identifies dual structural mimicry. 
Nat Commun, 9, pp. 4266 - 4266, 2018.

Experimental Information:

SOLUTION NMR

Cell Constants:

a =   b =   c = (Ångstroms)

α =   β =   γ = (degrees)

Number of Models:

Number of Models: 10 Structures

Sample Details:

0.5 mM TAR RNA with deuterated NTPs in a combo of either AC, GU, or GA, 0.5 mM Tat RNA Binding Domain, 90% H2O/10% D2O 90% H2O/10% D2O