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NDB ID: 6MFN    PDB ID: 6MFN 


Title:

HUMAN ARGONAUTE2-MIR-27A BOUND TO HSUR1 TARGET RNA

Molecular Description:

Protein argonaute-2/RNA Complex

Deposited:

2018-09-11

Released:

2019-08-07

Structural Keywords:

A DOUBLE HELIX

Nucleic Acid Sequence:

Click to show/hide 2 nucleic acid sequences

Protein Sequence:

Click to show/hide 1 protein sequences

Primary Citation:

Sheu-Gruttadauria, J., Pawlica, P., Klum, S.M., Wang, S., Yario, T.A., Schirle Oakdale, N.T., Steitz, J.A., MacRae, I.J.
Structural Basis for Target-Directed MicroRNA Degradation. 
Mol.Cell, , pp. - , 2019.

Experimental Information:

X-RAY DIFFRACTION

Space Group:

P 2 21 21

Cell Constants:

a = 66.948   b = 104.212   c = 152.858 (Ångstroms)

α = 90.0   β = 90.0   γ = 90.0 (degrees)

Refinement:

The structure was refined using the PHENIX program. The R value is 0.2109 for 37587 reflections in the resolution range 28.59 to 2.5 Ångstroms with Fobs >  1.35 sigma(Fobs) and with I >  0.0 sigma(I)