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NDB ID: 6MIK    PDB ID: 6MIK 


Title:

CRYSTAL STRUCTURE OF HOST-GUEST COMPLEX WITH PP HACHIMOJI DNA

Molecular Description:

N-terminal fragment of MMLV reverse transcriptase/DNA Complex

Deposited:

2018-09-19

Released:

2019-02-27

Structural Keywords:

B DOUBLE HELIX

Nucleic Acid Sequence:

Click to show/hide 2 nucleic acid sequences

Protein Sequence:

Click to show/hide 1 protein sequences

Primary Citation:

Hoshika, S., Leal, N.A., Kim, M.J., Kim, M.S., Karalkar, N.B., Kim, H.J., Bates, A.M., Watkins Jr., N.E., SantaLucia, H.A., Meyer, A.J., DasGupta, S., Piccirilli, J.A., Ellington, A.D., SantaLucia Jr., J., Georgiadis, M.M., Benner, S.A.
Hachimoji DNA and RNA: A genetic system with eight building blocks. 
Science, 363, pp. 884 - 887, 2019.

Experimental Information:

X-RAY DIFFRACTION

Space Group:

P 21 21 2

Cell Constants:

a = 55.152   b = 145.849   c = 46.849 (Ångstroms)

α = 90.0   β = 90.0   γ = 90.0 (degrees)

Refinement:

The structure was refined using the PHENIX program. The R value is 0.215 for 42253 reflections in the resolution range 39.416 to 1.7 Ångstroms with Fobs >  1.34 sigma(Fobs) and with I >  0.0 sigma(I)