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NDB ID: 6MKN    PDB ID: 6MKN 


Title:

STRUCTURE OF THE THERMUS THERMOPHILUS 30S RIBOSOMAL SUBUNIT COMPLEXED WITH AN INOSINE (I34) MODIFIED ANTICODON STEM LOOP (ASL) OF ESCHERICHIA COLI TRANSFER RNA ARGININE 2 (TRNAARG2) BOUND TO AN MRNA WITH AN CGU-CODON IN THE A-SITE AND PAROMOMYCIN

Molecular Description:

Ribosome

Deposited:

2018-09-25

Released:

2019-04-24

Nucleic Acid Sequence:

Click to show/hide 3 nucleic acid sequences

Protein Sequence:

Click to show/hide 20 protein sequences

Primary Citation:

Vangaveti, S., Cantara, W.A., Spears, J.L., DeMirci, H., Murphy IV, F.V., Ranganathan, S.V., Sarachan, K.L., Agris, P.F.
A Structural Basis for Restricted Codon Recognition Mediated by 2-thiocytidine in tRNA Containing a Wobble Position Inosine. 
J.Mol.Biol., 432, pp. 913 - 929, 2020.

Experimental Information:

X-RAY DIFFRACTION

Space Group:

P 41 21 2

Cell Constants:

a = 403.73   b = 403.73   c = 177.42 (Ångstroms)

α = 90.0   β = 90.0   γ = 90.0 (degrees)

Refinement:

The structure was refined using the PHENIX program. The R value is 0.2031 for 318813 reflections in the resolution range 49.804 to 3.46 Ångstroms with Fobs >  0.87 sigma(Fobs) and with I >  0.0 sigma(I)