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NDB ID: 6ML6    PDB ID: 6ML6 


Title:

ZBTB24 ZINC FINGERS 4-8 WITH 19+1MER DNA OLIGONUCLEOTIDE (SEQUENCE 4 WITH A CPA 5MC MODIFICATION)

Molecular Description:

CCAAT/enhancer-binding protein beta
16-bp methylated oligonucleotide

Deposited:

2018-09-26

Released:

2019-07-03

Structural Keywords:

B DOUBLE HELIX

Nucleic Acid Sequence:

Click to show/hide 2 nucleic acid sequences

Protein Sequence:

Click to show/hide 1 protein sequences

Primary Citation:

Ren, R., Hardikar, S., Horton, J.R., Lu, Y., Zeng, Y., Singh, A.K., Lin, K., Coletta, L.D., Shen, J., Lin Kong, C.S., Hashimoto, H., Zhang, X., Chen, T., Cheng, X.
Structural basis of specific DNA binding by the transcription factor ZBTB24. 
Nucleic Acids Res., 47, pp. 8388 - 8398, 2019.

Experimental Information:

X-RAY DIFFRACTION

Space Group:

P 1 21 1

Cell Constants:

a = 46.163   b = 68.244   c = 49.259 (Ångstroms)

α = 90.0   β = 92.9   γ = 90.0 (degrees)

Refinement:

The structure was refined using the PHENIX program. The R value is 0.2023 for 45091 reflections in the resolution range 28.038 to 1.54 Ångstroms with Fobs >  1.34 sigma(Fobs) and with I >  0.0 sigma(I)