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NDB ID: 6MWN    PDB ID: 6MWN 


Title:

CRYSTAL STRUCTURE OF HEPATITIS A VIRUS IRES DOMAIN V IN COMPLEX WITH FAB HAVX

Molecular Description:

Fab HAVx Heavy Chain
Fab HAVx Light Chain/RNA Complex

Deposited:

2018-10-29

Released:

2019-08-14

Nucleic Acid Sequence:

Click to show/hide 1 nucleic acid sequences

Protein Sequence:

Click to show/hide 2 protein sequences

Primary Citation:

Koirala, D., Shao, Y., Koldobskaya, Y., Fuller, J.R., Watkins, A.M., Shelke, S.A., Pilipenko, E.V., Das, R., Rice, P.A., Piccirilli, J.A.
A conserved RNA structural motif for organizing topology within picornaviral internal ribosome entry sites. 
Nat Commun, 10, pp. 3629 - 3629, 2019.

Experimental Information:

X-RAY DIFFRACTION

Space Group:

P 21 2 21

Cell Constants:

a = 74.149   b = 100.582   c = 236.594 (Ångstroms)

α = 90.0   β = 90.0   γ = 90.0 (degrees)

Refinement:

The structure was refined using the PHENIX program. The R value is 0.1856 for 42533 reflections in the resolution range 29.607 to 2.838 Ångstroms with Fobs >  1.38 sigma(Fobs) and with I >  0.0 sigma(I)