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NDB ID: 6ND6    PDB ID: 6ND6 


Title:

CRYSTAL STRUCTURE OF THE THERMUS THERMOPHILUS 70S RIBOSOME IN COMPLEX WITH ERYTHROMYCIN AND BOUND TO MRNA AND A-, P-, AND E-SITE TRNAS AT 2.85A RESOLUTION

Molecular Description:

Ribosome

Deposited:

2018-12-13

Released:

2019-02-20

Nucleic Acid Sequence:

Click to show/hide 6 nucleic acid sequences

Protein Sequence:

Click to show/hide 49 protein sequences

Primary Citation:

Svetlov, M.S., Plessa, E., Chen, C.W., Bougas, A., Krokidis, M.G., Dinos, G.P., Polikanov, Y.S.
High-resolution crystal structures of ribosome-bound chloramphenicol and erythromycin provide the ultimate basis for their competition. 
RNA, 25, pp. 600 - 606, 2019.

Experimental Information:

X-RAY DIFFRACTION

Space Group:

P 21 21 21

Cell Constants:

a = 210.05   b = 448.09   c = 621.49 (Ångstroms)

α = 90.0   β = 90.0   γ = 90.0 (degrees)

Refinement:

The structure was refined using the PHENIX program. The R value is 0.2522 for 1330157 reflections in the resolution range 224.045 to 2.85 Ångstroms with Fobs >  1.34 sigma(Fobs) and with I >  0.0 sigma(I)