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NDB ID: 6O6P    PDB ID: 6O6P 


Title:

STRUCTURE OF THE REGULATOR FASR FROM MYCOBACTERIUM TUBERCULOSIS IN COMPLEX WITH DNA

Molecular Description:

TetR family transcriptional regulator/DNA Complex

Deposited:

2019-03-07

Released:

2020-03-11

Structural Keywords:

B DOUBLE HELIX

Nucleic Acid Sequence:

Click to show/hide 2 nucleic acid sequences

Protein Sequence:

Click to show/hide 1 protein sequences

Primary Citation:

Lara, J., Trajtenberg, F., Larrieux, N., Gramajo, H., Buschiazzo, A.
Crystal structures of FasR uncover the mechanisms of long fatty acyl-CoA sensing and transcriptional activation switching in Mycobacterium tuberculosis
To be Published, , pp. - , 0.

Experimental Information:

X-RAY DIFFRACTION

Space Group:

C 2 2 21

Cell Constants:

a = 61.697   b = 174.68   c = 158.169 (Ångstroms)

α = 90.0   β = 90.0   γ = 90.0 (degrees)

Refinement:

The structure was refined using the PHENIX program. The R value is 0.2919 for 6431 reflections in the resolution range 39.066 to 3.851 Ångstroms with Fobs >  1.35 sigma(Fobs) and with I >  0.0 sigma(I)