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NDB ID: 6OD5    PDB ID: 6OD5 


Title:

HUMAN TCF4 C-TERMINAL BHLH DOMAIN IN COMPLEX WITH 12-BP OLIGONUCLEOTIDE CONTAINING E-BOX SEQUENCE WITH 5-CARBOXYLCYTOSINES

Molecular Description:

Transcription factor 4/DNA Complex

Deposited:

2019-03-25

Released:

2019-05-29

Structural Keywords:

B DOUBLE HELIX

Nucleic Acid Sequence:

Click to show/hide 1 nucleic acid sequences

Protein Sequence:

Click to show/hide 1 protein sequences

Primary Citation:

Yang, J., Horton, J.R., Li, J., Huang, Y., Zhang, X., Blumenthal, R.M., Cheng, X.
Structural basis for preferential binding of human TCF4 to DNA containing 5-carboxylcytosine. 
Nucleic Acids Res., , pp. - , 2019.

Experimental Information:

X-RAY DIFFRACTION

Space Group:

P 1

Cell Constants:

a = 44.677   b = 44.757   c = 54.64 (Ångstroms)

α = 78.63   β = 78.88   γ = 79.27 (degrees)

Refinement:

The structure was refined using the PHENIX program. The R value is 0.2364 for 24247 reflections in the resolution range 36.661 to 2.05 Ångstroms with Fobs >  1.98 sigma(Fobs) and with I >  0.0 sigma(I)