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NDB ID: 6OEB    PDB ID: 6OEB 


Title:

CRYSTAL STRUCTURE OF HMCES SRAP DOMAIN IN COMPLEX WITH 3' OVERHANG DNA

Molecular Description:

Embryonic stem cell-specific 5-hydroxymethylcytosine-binding protein

Deposited:

2019-03-27

Released:

2019-04-10

Nucleic Acid Sequence:

Click to show/hide 2 nucleic acid sequences

Protein Sequence:

Click to show/hide 1 protein sequences

Primary Citation:

Halabelian, L., Ravichandran, M., Li, Y., Zeng, H., Rao, A., Aravind, L., Arrowsmith, C.H.
Structural basis of HMCES interactions with abasic DNA and multivalent substrate recognition. 
Nat.Struct.Mol.Biol., 26, pp. 607 - 612, 2019.

Experimental Information:

X-RAY DIFFRACTION

Space Group:

I 1 2 1

Cell Constants:

a = 55.728   b = 51.151   c = 149.21 (Ångstroms)

α = 90.0   β = 92.77   γ = 90.0 (degrees)

Refinement:

The structure was refined using the REFMAC program. The R value is 0.2074 for 23486 reflections in the resolution range 48.38 to 2.1 Ångstroms with Fobs >  0.0 sigma(Fobs) and with I >  0.0 sigma(I)