A Portal for Three-dimensional Structural Information about Nucleic Acids
As of 15-Jan-2020 number of released structures: 10589
Search for released structures

NDB ID: 6P0B    PDB ID: 6P0B 


Title:

HUMAN DNA LIGASE 1 (E346A/E592A) BOUND TO AN ADENYLATED, DIDEOXY TERMINATED DNA NICK WITH 200 MM MG2+

Molecular Description:

DNA ligase 1/DNA Complex

Deposited:

2019-05-16

Released:

2019-12-11

Structural Keywords:

B DOUBLE HELIX

Nucleic Acid Sequence:

Click to show/hide 3 nucleic acid sequences

Protein Sequence:

Click to show/hide 1 protein sequences

Primary Citation:

Tumbale, P.P., Jurkiw, T.J., Schellenberg, M.J., Riccio, A.A., O'Brien, P.J., Williams, R.S.
Two-tiered enforcement of high-fidelity DNA ligation. 
Nat Commun, 10, pp. 5431 - 5431, 2019.

Experimental Information:

X-RAY DIFFRACTION

Space Group:

P 21 21 21

Cell Constants:

a = 71.866   b = 101.398   c = 115.606 (Ångstroms)

α = 90.0   β = 90.0   γ = 90.0 (degrees)

Refinement:

The structure was refined using the PHENIX program. The R value is 0.1717 for 43011 reflections in the resolution range 41.428 to 2.203 Ångstroms with Fobs >  1.34 sigma(Fobs) and with I >  0.0 sigma(I)