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NDB ID: 6P93    PDB ID: 6P93 


Title:

HUMAN APE1 K98A AP-ENDONUCLEASE PRODUCT COMPLEX

Molecular Description:

DNA-(apurinic or apyrimidinic site) lyase/DNA Complex

Deposited:

2019-06-09

Released:

2020-01-01

Structural Keywords:

B DOUBLE HELIX

Nucleic Acid Sequence:

Click to show/hide 3 nucleic acid sequences

Protein Sequence:

Click to show/hide 1 protein sequences

Primary Citation:

McNeill, D.R., Whitaker, A.M., Stark, W.J., Illuzzi, J.L., McKinnon, P.J., Freudenthal, B.D., Wilson, D.M.
Functions of the major abasic endonuclease (APE1) in cell viability and genotoxin resistance. 
Mutagenesis, , pp. - , 2019.

Experimental Information:

X-RAY DIFFRACTION

Space Group:

P 1

Cell Constants:

a = 44.351   b = 60.493   c = 72.62 (Ångstroms)

α = 83.72   β = 79.66   γ = 88.46 (degrees)

Refinement:

The structure was refined using the PHENIX program. The R value is 0.1745 for 58444 reflections in the resolution range 24.966 to 2.1 Ångstroms with Fobs >  1.97 sigma(Fobs) and with I >  0.0 sigma(I)