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NDB ID: 6P94    PDB ID: 6P94 


Title:

HUMAN APE1 C65A AP-ENDONUCLEASE PRODUCT COMPLEX

Molecular Description:

DNA-(apurinic or apyrimidinic site) lyase/DNA Complex

Deposited:

2019-06-09

Released:

2020-01-01

Structural Keywords:

B DOUBLE HELIX

Nucleic Acid Sequence:

Click to show/hide 3 nucleic acid sequences

Protein Sequence:

Click to show/hide 1 protein sequences

Primary Citation:

McNeill, D.R., Whitaker, A.M., Stark, W.J., Illuzzi, J.L., McKinnon, P.J., Freudenthal, B.D., Wilson, D.M.
Functions of the major abasic endonuclease (APE1) in cell viability and genotoxin resistance. 
Mutagenesis, 35, pp. 27 - 38, 2020.

Experimental Information:

X-RAY DIFFRACTION

Space Group:

P 1

Cell Constants:

a = 43.585   b = 60.459   c = 71.924 (Ångstroms)

α = 83.69   β = 79.47   γ = 88.74 (degrees)

Refinement:

The structure was refined using the PHENIX program. The R value is 0.1894 for 36463 reflections in the resolution range 24.579 to 2.09 Ångstroms with Fobs >  1.47 sigma(Fobs) and with I >  0.0 sigma(I)