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NDB ID: 6PLC    PDB ID: 6PLC 


Title:

STRUCTURE OF HUMAN DNA POLYMERASE ETA COMPLEXED WITH 8OA IN THE TEMPLATE BASE PAIRED WITH INCOMING NON-HYDROLYZABLE GTP

Molecular Description:

DNA polymerase beta/DNA Complex

Deposited:

2019-06-30

Released:

2020-04-22

Structural Keywords:

B DOUBLE HELIX

Nucleic Acid Sequence:

Click to show/hide 2 nucleic acid sequences

Protein Sequence:

Click to show/hide 1 protein sequences

Primary Citation:

Koag, M.C., Jung, H., Lee, S.
Mutagenesis mechanism of the major oxidative adenine lesion 7,8-dihydro-8-oxoadenine. 
Nucleic Acids Res., , pp. - , 2020.

Experimental Information:

X-RAY DIFFRACTION

Space Group:

P 61

Cell Constants:

a = 98.447   b = 98.447   c = 81.856 (Ångstroms)

α = 90.0   β = 90.0   γ = 120.0 (degrees)

Refinement:

The structure was refined using the REFMAC program. The R value is 0.1834 for 14240 reflections in the resolution range 20.0 to 2.5 Ångstroms with Fobs >  0.0 sigma(Fobs) and with I >  0.0 sigma(I)