A Portal for Three-dimensional Structural Information about Nucleic Acids
As of 12-Jan-2022 number of released structures: 11872
Search for released structures

NDB ID: 6PY8    PDB ID: 6PY8 


Title:

CRYSTAL STRUCTURE OF THE RBPJ-NOTCH1-NRARP TERNARY COMPLEX BOUND TO DNA

Molecular Description:

Notch-regulated ankyrin repeat-containing protein
Recombining binding protein suppressor of hairless
Neurogenic locus notch homolog protein 1/DNA Complex

Deposited:

2019-07-29

Released:

2019-08-14

Structural Keywords:

B DOUBLE HELIX

Nucleic Acid Sequence:

Click to show/hide 2 nucleic acid sequences

Protein Sequence:

Click to show/hide 3 protein sequences

Primary Citation:

Jarrett, S.M., Seegar, T.C.M., Andrews, M., Adelmant, G., Marto, J.A., Aster, J.C., Blacklow, S.C.
Extension of the Notch intracellular domain ankyrin repeat stack by NRARP promotes feedback inhibition of Notch signaling. 
Sci.Signal., 12, pp. - , 2019.

Experimental Information:

X-RAY DIFFRACTION

Space Group:

P 21 21 21

Cell Constants:

a = 79.88   b = 103.65   c = 301.42 (Ångstroms)

α = 90.0   β = 90.0   γ = 90.0 (degrees)

Refinement:

The structure was refined using the PHENIX program. The R value is 0.27 for 26212 reflections in the resolution range 48.46 to 3.75 Ångstroms with Fobs >  1.43 sigma(Fobs) and with I >  0.0 sigma(I)